Finding flavor genes
نویسندگان
چکیده
منابع مشابه
Finding schizophrenia genes.
Genetic epidemiological studies suggest that individual variation in susceptibility to schizophrenia is largely genetic, reflecting alleles of moderate to small effect in multiple genes. Molecular genetic studies have identified a number of potential regions of linkage and 2 associated chromosomal abnormalities, and accumulating evidence favors several positional candidate genes. These findings...
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enough that they might represent two portions of the same gene. Of the 215 protein-coding regions reported by Bowman et al., GlimmerM automatically finds 214 of them. (An earlier version of GlimmerM was provided to the annotators of chromosome 3.) The only gene missed is a short hypothetical protein (PFC0360w, 114 amino acids) with no homology to any known gene. Finally, given that chromosome 3...
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We present an automated method of identifying communities of functionally related genes from the biomedical literature. These communities encapsulate human gene and protein interactions and identify groups of genes that are complementary in their function. We use graphs to represent the network of gene cooccurrences in articles mentioning particular keywords, and find that these graphs consist ...
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New studies have substantially advanced our understanding of the genetic architecture of schizophrenia, but we are far from identifying the underlying mutations. We may require new approaches to understand the biological implications of insights into the genetics of psychiatric disease.
متن کاملa tool for finding genes
Problem: In “Classical Linkage Mapping” we showed how to construct maps that give the order of and genetic distances between gene pairs for variable, single-gene traits that are linked (lie on the same homologous chromosome pair). Prominent among the variable, single-gene tmits of hu~mans are inherited diseases, Several thousand such genetic disorders have been identified, and many of the genes...
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ژورنال
عنوان ژورنال: Genome Biology
سال: 2000
ISSN: 1474-760X
DOI: 10.1186/gb-2000-1-2-reports0057